Functional results of exclusive interventional radiotherapy (brachytherapy) in the treatment of nasal vestibule carcinomas

Purpose Surgery, external beam radiotherapy (EBRT), and interventional (IRT, BrachyTherapy BT) are the current therapeutic options for nose vestibule (NV) squamous cell carcinoma (SCC). In this article, we evaluate functional parameters of patients affected by SCCs NV, primarily treated interstitial IRT comparing them with healthy controls intensity-modulated EBRT. Methods Ten using (group 1), 10 eight EBRT 2) on region were submitted to clinical evaluation (with NOSE scale score), rhinomanometry, olfactory testing, nasal citology, mucociliary clearance through saccharine test. Results No long-term skin or cartilaginous toxicity recorded. The olfactometry threshold discrimination identification TDI is lower in EB group. mean score was significantly higher group 2 than 1 (p < 0.05). distribution cytologic patterns resulted different as well. Patients have a impaired clearance, time transport stained marker, which more double those 0.001). Conclusions Nasal function cytological findings better, substantially preserved, EBRT, bringing new relevant evidence establishment standard treatment primary lesion cT1 cT2 -Wang staging NV SCCs.